- protein post-translational modifications in signal transduction
Our lab has been focusing on different protein post-translational modifications including phosphorylation, acetylation, and ubiquitination/sumoylation during signal transduction. We found that acetylation and deacetylation are critical events involved in the regulation of the JAK-STAT signal pathway. Constitutively acetylated STAT proteins may cause cancer cell metastasis.
This site contains materials and links that are designed for undergraduate level molecular biology and bioinformatics lecture and lab courses. These include assignments, tools to analyze DNA and protein sequences, links to molecular models and lecture materials.
Laboratory of Richard Gronostajski, SUNY-Buffalo, NFI transcription factors
Site describes work on the Nuclear Factor I (NFI) transcription factor family in transcription and development.
Biological Language Conference
Integration of language technologies in bioinformatics/computational biology research. The biology-language analogy enables novel applications of language technologies to the biology domain, but is to a great extent overlapping with existing other computational biology/bioinformatics applications. The purpose of the Biological Language Conference is to facilitate scientific exchange between researchers using the language analogy approach directly and researchers using other approaches.
Life science reagents supplier
World wide supply centre of 100 000 life science reagents with transparant pricing structure and next fast delivery. Antibodies, Neurobiology, Apoptosis, Molecular Biology, Immunology.
The Cellular and Molecular Biochemistry Laboratory conducts research in signaling in normal and cancer cell growth. The key signal under investigation is protein kinase CK2, and the cancer focus is on prostate cancer and squamous cell carcinoma of head and neck.
THE Medical Biochemistry Page
This site is designed as a review for Medical Biochemistry but is equally suitable for any individual seeking review materials for Biochemistry
Low Dose Radiation Research
The DOE Low Dose Radiation Research Program is funding basic research to determine the responses induced by radiation exposures at doses of 10cGy and below. The research is international in nature and will provide a scientific underpinning for future radiation protection standards. Currently about 60% of the projects are funded through Universities and 30% through DOE National Laboratories. The funding is focused to determine the mechanistic basis for the interaction of low doses of radiation with biological systems. These mechanistic studies are focused on DNA damage and repair, endogenous vs. radiation-induced oxidative damage, adaptive responses, bystander effects, genomic instability and genetic susceptibility. The research is conducted at all levels of biological organization from molecular to organism. Detailed information is available on this Website on the individual projects funded, abstracts of past research, publications that have resulted to date from this research and past and future directions of the Program. To ensure that the data are carefully and appropriately evaluated, the Program is also funding projects on mathematical modeling. These projects help identify research needs and integrate the basic data into useful models of radiation cancer risks. In the future, the data from the DOE Low Dose Radiation Research Program will support molecular and genetic epidemiology, generate biologically-based risk models and help define the role that individual genetic susceptibility play in radiation-induced cancer risk. Such research will help insure that the standards are adequate and appropriate.
Oklahoma State University Microarray Core Facility
This Facility functions to stimulate the competitiveness of microarray research activities at Oklahoma State University by providing access to advanced analysis instrumentation, software and expertise.
Professor Tamar Schlick's Computational Biology Laboratory at New York University
The Schlick Lab focuses on computational structural biology and RNA genomics. Current research in structural biology involves development of structural models and efficient algorithms for simulating proteins and complexes, including DNA polymerase beta and chromatin. The lab's RNA genomics work involves identification of functional RNA motifs and design of novel RNA structures aided by graph theory analysis. The Schlick Lab webpage highlights aspects of the group's research, software, publication, and RNA-As-Graphs database, as well as research and training opportunities.
International Conference on Structural and Molecular Biology
International Conference on Structural and Molecular Biology. The conferences aim to bring together scientists from the fields of X-ray crystallography, NMR spectroscopy, molecular biology, structure prediction, computer modeling and microscopy. The fourth conference has covered all these areas, and in addition featured a session on the industrial use of these techniques in the design of novel biologically active molecules, as well as a session on Structural Genomics. The next conference is scheduled for 2005.
NON-CANONICAL BASE PAIR DATABASE
Database of non-standard base-base interactions seen in RNA structures that have been determined at atomic resolution.
MCW Proteomics Center
The aim of the project is to develop mass spectrometric methodologies and protein separation techniques for the quantitative analysis of the entire proteome of a single cell. Ultimately we will be studying angiogenesis in a unique model system - consomic rat strains (chromosome substitution strains) developed by the MCW PGA project.
Bioinformatics and Yeast biology
On the bioinformatics end we are interested in the computational prediction of essential genes and advancements in homology modeling. On the biology site our research is focused on ovarian cancer and folate metabolism using yeast as a model system
AptaRes - the MonoLex experts isolate aptamer for your target
AptaRes is specialized in the preparation of oligonucleotides with high affinity to a target molecule. In contrast to immunoglobulins these aptamers consist of nucleic acids. We produce aptamers quickly with the one-step MonoLex™ technology from a combinatory library. We also develop aptamer based applications according to your needs in the fields of analytics, biosensors, cell biology, glycomics, metabolics, proteomics or toxicology.
German Society for Biochemistry and Molecular Biology (GBM)
The GBM is the association of about 5500 (mainly German) scientist working in the fields of Biochemistry and Molecular Biology. The GBM-homepage offers a wide range of information about the society, meetings, universities, student activities and public affairs related to the topic.
Keystone Symposia on Molecular and Cellular Biology
Keystone Symposia, a non-profit organization dedicated to Connecting the Scientific Community for the benefit of society, conducts scientific conferences on biomedical and life science topics in relaxing environments that catalyze information exchange and networking.
Molecular Research Center, Inc.
Molecular Research Center, Inc., founded by P. Chomczynski, develops and manufactures RNA and DNA isolation reagents for RT-PCR, PCR and microarrays. Products include TRI Reagent for RNA isolation and DNAzol for genomic DNA isolation in cells, tissues, liquid, blood, plant and bacterial samples.
PCR kits and reagents for molecular biology
Sacace develops and sells through distributors more than 100 complete PCR kits for human, veterinary, food diagnostic and molecular biology reagents
Mobix Lab, McMaster University
central facility that provides service and support in Oligo synthesis, DNA sequencing and fragment analysis.
NCCR Structural Biology
The NCCR Structural Biology is an Swiss research initiative. Our focus is on membrane proteins and supramolecular complexes/interactions. The web site describes our research highlights, education program and more.
Akif Uzman Home Page
Faculty home page for students in the life sciences at the University of Houston - Downtown
Peptide synthesis, Fmoc amino acids manufacturer
Xi'an Huachen Bio-Tech Co.,Ltd.. located in Xi'an, China, is a peptide technology based company that specializes in manufacturing of peptides reagents, resins and their derivatives . Huachen Bio offers reagents for the synthesis of peptides. These include high quality Fmoc and Boc amino acids, reagents, and resins at the most competitive prices in the industry. The products include : Amino Acids Derivatives Coupling Reagents Resins Peptides Likers for Solid Phase synthesis Protecting Reagents and Peptide Coupling Others ======================== Xi'an Huachen Bio-Tech Co.,Ltd.. Fax:86-029-86030234 Tel:86-029-86030149 Contact: Max Meng E-mail:email@example.com Http://www.west-chemical.com
Makers of software with a restriction enzyme database to design experiments and produce high quality graphics.
International Conference on Molecular Structural Biology
Links to previous conferences and details of the fifth held for five days in Vienna, Austria.
Molecular Biology Web Book
Chapters include Cells and Viruses, Protein Structure and Function, Nucleic Acids, Genomics and Proteomics, Cell Signaling and Apoptosis, Biotechnology and Bioinformatics with introduction to Genes and Disease. Authors include Alberts and Lodish, based in Slingerlands, NY.
Databases and Search Tools
Biology databases and search tools, links to many useful sites.
Australasian Association of Clinical Biochemists
Gene Expression in Tooth
Overview of expression of different genes in the developing tooth.